As Senior Scientist, Process Modelling within our Global CMC Development team, you'll drive innovation in biopharmaceutical process development by developing and deploying cutting-edge mechanistic, hybrid, and data-driven modelling solutions for downstream unit operations. You'll work at the intersection of process engineering and data science, translating complex mathematical models into practical tools that optimize the development and manufacturing of next-generation medicines that improve patients' lives worldwide. Ready to get started?
About Sanofi:
We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.
Your responsibilities:
- As part of matrix project teams, develop and deploy mechanistic, hybrid and data-driven modelling solutions to support downstream process development activities for a broad range of biopharmaceuticals.
- Use programming languages such as Python, MATLAB, R to translate complex mathematical models into clean and reusable codes for model use and implementation.
- In coordination with the process development group and working closely with the Data Science team, design and analyze targeted experiments required to calibrate and verify model performance.
- Act as a change agent to support the implementation of process modelling in established process development workflows for targeted downstream unit operations.
- Document progress against deliverables with rigorous scientific communication via technical presentations, reports and, when appropriate, scientific publications.
- Track progress against deliverables and maintain a communication plan with key stakeholders and partners across departments.
For this position, knowledge in biologics downstream unit operations (chromatography, viral inactivation, ultrafiltration/diafiltration) is required. This is an exciting opportunity to demonstrate the benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.
Basic Qualifications:
- PhD in Chemical, Biochemical Engineering or Bioengineering or MSc with 4 years of industrial experience.
- Research or industrial track record of developing process models for downstream unit operations for biologics such as affinity/ion exchange chromatography, ultra/ nano / tangential flow filtration for process design, scale-up, scale-down and/or process control purposes.
- Demonstrated ability to translate mathematical models into computer programs using programming languages such as MATLAB, R, Python or similar.
- Domain knowledge in Biology with industrial or academic experience in downstream process development and/or manufacturing.
Preferred Qualifications:
- Demonstrated knowledge and application of Machine Learning / Multivariate analysis methodologies to biological processes.
- Experience with downstream process simulation software such as CADET, gPROMS or goSilico
- Experience in continuous bioprocess manufacture with associated Model Predictive Control (MPC).
- Solid track record of publications in the field of process modelling/process simulation in peer reviewed journals.
Beyond technical skills you will also have a solid track record in project management with an ability to communicate with transparency with your peers and with senior stakeholders.
This cross functional role will require intellectual agility to work across site/function boundaries in Sanofi's global CMC organization.
Why Join Us?
- Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
- Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
- Help improve the lives of millions of people globally by making drug development quicker and more effective.
- Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields to spark new ideas and drive breakthroughs.
- Accelerate your professional development with structured career paths designed for both scientific and leadership advancement. Grow in ways you never imagined through bold moves that stretch your potential, cross moves into other business areas, and short-term gigs that build your scientific expertise.
- Join a workplace where diversity, equity, and inclusion are at the core, with Employee Resource Groups and leadership programs that celebrate every voice.
- Achieve genuine work-life balance in a supportive R&D environment.
- Enjoy outstanding benefits, including flexible working options, comprehensive healthcare, and well-being programs designed to help you thrive.
Diversity und Inklusion sind in den Grundwerten von Sanofi verankert und spiegeln sich in unserer Arbeitsweise wider. Wir respektieren die Vielfalt unserer Belegschaft in Hinsicht auf ihre Herkunft, Erfahrungen und Lebensweisen. Wir erkennen die Bereicherung, die diese Vielfalt birgt, und fördern Inklusion sowie eine Arbeitsumgebung, in der diese Unterschiede sich weiter entwickeln können, zur Stärkung des Lebens unserer Mitarbeiter, Patienten und Kunden.
The salary range for this position is :€79104,00 - €105472
Die endgültige Vergütung wird auf Grundlage nachgewiesener Erfahrung, Fähigkeiten, Standort und weiterer relevanter Faktoren bestimmt. Mitarbeitende können berechtigt sein, an den Mitarbeitenden Leistungsprogrammen des Unternehmens teilzunehmen.
